Stem Cell Differentiation as a Non-Markov Stochastic Process
نویسندگان
چکیده
منابع مشابه
Stem Cell Differentiation as a Non-Markov Stochastic Process
Pluripotent stem cells can self-renew in culture and differentiate along all somatic lineages in vivo. While much is known about the molecular basis of pluripotency, the mechanisms of differentiation remain unclear. Here, we profile individual mouse embryonic stem cells as they progress along the neuronal lineage. We observe that cells pass from the pluripotent state to the neuronal state via a...
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2017
ISSN: 2405-4712
DOI: 10.1016/j.cels.2017.08.009